Mutagenesis of Neisseria gonorrhoeae: absence of error-prone repair

1 October 1984

journal article
research article
Published by American Society for Microbiology in Journal of Bacteriology

Vol. 160 (1) , 288-293
https://doi.org/10.1128/jb.160.1.288-293.1984

Abstract

The lethal and mutagenic effects of various mutagens on N. gonorrhoeae were investigated. Lethality studies demonstrated that N. gonorrhoeae was relatively sensitive to ethyl methanesulfonate, UV light and methyl methanesulfonate. Although N. gonorrhoeae was readily mutated by ethyl methanesulfonate and N-methyl-N''-nitro-N-nitrosoguanidine for the 3 genetic markers assayed, no increase in the mutation frequency was observed for any of the selective markers after UV irradiation or methyl methanesulfonate treatment. These results suggest that N. gonorrhoeae lacks an error-prone repair mechanism.

This publication has 38 references indexed in Scilit:

MUTATIONAL SPECIFICITY IN BACTERIA
Annual Review of Genetics, 1983
Genetic effects of N-methyl-N′-nitro-N-nitrosoguanidine and its homologs
Mutation Research/Reviews in Genetic Toxicology, 1982
Mutagenesis during transformation of Bacillus subtilis II. An increase in chemically-induced mutations during competency
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1981
Influence of DNA-repair deficiencies on MMS- and EMS-induced mutagenesis in Escherichia coli K-12
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1981
Lack of SOS repair in Streptococcus pneumoniae
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1980
Evidence that UV-inducible error-prone repair is absent in Haemophilus influenzae Rd, with a discussion of the relation to erro-prone repair of alkylating-agent damage
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1977
Caffeine
Mutation Research/Reviews in Genetic Toxicology, 1977
The Biochemistry of Mutagenesis
Annual Review of Biochemistry, 1976
Accurate repair of ultraviolet-induced damage in Micrococcus radiodurans
Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, 1974
TRANSFORMATION OF BIOCHEMICALLY DEFICIENT STRAINS OF BACILLUS SUBTILIS BY DEOXYRIBONUCLEATE
Proceedings of the National Academy of Sciences, 1958