Hyaluronan serves a novel role in airway mucosal host defense
Open Access
- 1 October 2001
- journal article
- research article
- Published by Wiley in The FASEB Journal
- Vol. 15 (12) , 2179-2186
- https://doi.org/10.1096/fj.01-0036com
Abstract
Enzymes secreted onto epithelial surfaces play a vital role in innate mucosal defense, but are believed to be steadily removed from the surface by mechanical actions. Thus, the amount and availabilit...Keywords
Funding Information
- National Institutes of Health (K01-03534)
- American Lung Association in Florida
- University of Miami
This publication has 42 references indexed in Scilit:
- Hyaluronic Acid in Cultured Ovine Tracheal Cells and Its Effect on Ciliary Beat Frequency In VitroJournal of Aerosol Medicine, 2000
- Mode of Ca2+ action on ciliary beat frequency in single ovine airway epithelial cellsThe Journal of Physiology, 1999
- Interplay between the NO pathway and elevated [Ca2+]i enhances ciliary activity in rabbit tracheaThe Journal of Physiology, 1999
- Overexpression of the hyaluronan receptor RHAMM is transforming and is also required for H-ras transformationCell, 1995
- Interaction between CD44 and hyaluronate is directly implicated in the regulation of tumor development.The Journal of Experimental Medicine, 1994
- Lung Hyaluronan as Assayed with a Biotinylated Hyaluronan-Binding ProteinExperimental Lung Research, 1994
- CD44 is the principal cell surface receptor for hyaluronateCell, 1990
- Studies in fetal wound healing, VII. Fetal wound healing may be modulated by hyaluronic acid stimulating activity in amniotic fluidJournal of Pediatric Surgery, 1990
- Hyaluronan Reflects the Pre-fibrotic Inflammation in Irradiated Rat Lung: Concomitant Analysis of Parenchymal Tissues and Bronchoalveolar LavageInternational Journal of Radiation Biology, 1990
- The Structure of Hyalobiuronic Acid and of Hyaluronic Acid from Umbilical Cord1,2Journal of the American Chemical Society, 1954