Structural Aspects of Plant Ferredoxin : NADP+Oxidoreductases
- 1 January 2004
- journal article
- Published by Springer Nature in Photosynthesis Research
- Vol. 81 (3) , 303-315
- https://doi.org/10.1023/b:pres.0000036884.57303.2e
Abstract
Ferredoxin reductase (FNR) is ubiquitous among photosynthetic organisms as the enzyme directly responsible for the generation of NADPH. Structural studies over the last 15 years have generated over 30 crystal structures of wild-type and mutant FNRs that have yielded a great deal of insight into its structure–function relations. These insights are summarized and combined to propose a structurally informed cycle for FNR catalysis in vivo.Keywords
This publication has 60 references indexed in Scilit:
- Mechanism of Coenzyme Recognition and Binding Revealed by Crystal Structure Analysis of Ferredoxin–NADP+ Reductase Complexed with NADP+Journal of Molecular Biology, 2002
- X-ray Crystal Structure of Benzoate 1,2-Dioxygenase Reductase from Acinetobacter sp. Strain ADP1Journal of Molecular Biology, 2002
- Four crystal structures of the 60 kDa flavoprotein monomer of the sulfite reductase indicate a disordered flavodoxin-like module 1 1Edited by R. HuberJournal of Molecular Biology, 2000
- Crystal Structure of NAD(P)H:Flavin Oxidoreductase from Escherichia coli,Biochemistry, 1999
- The crystal structure of NADPH: Ferredoxin reductase from azotobacter vinelandiiProtein Science, 1998
- The three-dimensional structure of flavodoxin reductase from Escherichia coli at 1.7 å resolutionJournal of Molecular Biology, 1997
- X-ray Structure of the Ferredoxin:NADP+Reductase from the CyanobacteriumAnabaenaPCC 7119 at 1.8 Å Resolution, and Crystallographic Studies of NADP+Binding at 2.25 Å ResolutionJournal of Molecular Biology, 1996
- Structural Studies on Corn Nitrate Reductase: Refined Structure of the CytochromebReductase Fragment at 2.5 Å, its ADP Complex and an Active-site Mutant and Modeling of the CytochromebDomainJournal of Molecular Biology, 1995
- Refined Crystal Structure of Spinach Ferredoxin Reductase at 1.7 Å Resolution: Oxidized, Reduced and 2′-Phospho-5′-AMP Bound StatesJournal of Molecular Biology, 1995
- Substrate binding and catalysis by glutathione reductase as derived from refined enzyme: Substrate crystal structures at 2Å resolutionJournal of Molecular Biology, 1989