pH induced changes in optical activity of guanine nucleosides
- 1 August 1968
- journal article
- Published by Wiley in FEBS Letters
- Vol. 1 (3) , 183-186
- https://doi.org/10.1016/0014-5793(68)80055-9
Abstract
Optical rotatory dispersion and circular dichroism have been used to investigate the protonation of guanosine and some of its analogues. An inversion of the principal Cotton effect and the dichroic band is observed below the acid pK. It is suggested that a conformational change from the anti form above the pK to the syn form below the pK occurs. The reasons why this change should occur only in guanosine and not in adenosine are discussed.Keywords
This publication has 23 references indexed in Scilit:
- Optical rotatory dispersion of purine cyclonucleosidesTetrahedron Letters, 1967
- Nucleotides. VII. Preparation and optical rotatory dispersion of some 9.beta.-D-ribofuranosyl-3,5'-purine cyclonucleosidesThe Journal of Organic Chemistry, 1967
- Optical rotatory dispersion, circular dichroism, and absorption studies on some naturally occurring ribonucleosides and related derivatives.Proceedings of the National Academy of Sciences, 1967
- The Conformation of Ribonucleosides in Solution. The Effect of Structure on the Orientation of the Base*Biochemistry, 1967
- Optical Rotatory Dispersion of Nucleic Acid Derivatives. VIII. The Conformation of Pyrimidine Nucleosides in Solution*Biochemistry, 1967
- Optical rotatory dispersion of anomeric pyrimidine nucleosidesTetrahedron Letters, 1966
- Optical rotatory dispersion of mononucleosides and 5′‐mononucleotidesBiopolymers, 1966
- The optical rotatory dispersion of purine nucleosidesBiochemical and Biophysical Research Communications, 1966
- The optical rotatory dispersion of pyrimidine nucleosidesBiochemical and Biophysical Research Communications, 1965
- Optical Rotatory Dispersion of DeoxyribonucleotidesJournal of the American Chemical Society, 1963