A NEW VIRUS SPECIFIED DETERMINANT OF HEPATITIS B SURFACE ANTIGEN
- 1 September 1975
- journal article
- Published by Wiley in Acta Pathologica Microbiologica Scandinavica Section B Microbiology
- Vol. 83B (3) , 295-297
- https://doi.org/10.1111/j.1699-0463.1975.tb00104.x
Abstract
One hundred and three samples from hepatitis B surface antigen (HBSAg) positive Californian blood donors were subtyped in immunodiffusion with respect to d/y, w/r and a21, a23, a3. Spur formation with a human antiserum indicated a previously unrecognized determinant q, which was detected in 96 sera (4 a21yw, 15 a23yw, 69 a21dw and 8 adr). Out of 8 sera which by spur formation were demonstrated to lack q, 7 were further subtyped (2 a21dw and 5 a3dw). Hence all 5 a3 dw specimens were demonstrated to lack q, thus indicating that q is specified by the virus. The possible relation of q to x with further implications for the specification of x is discussed.Keywords
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