Electrokinetic mechanism of miniature postsynaptic potentials.
- 1 May 1966
- journal article
- research article
- Published by Proceedings of the National Academy of Sciences in Proceedings of the National Academy of Sciences
- Vol. 55 (5) , 1214-1217
- https://doi.org/10.1073/pnas.55.5.1214
Abstract
A model of the presynaptic mechanism determining the frequency of MEPP''s (miniature end-plate potentials) in neuromuscular junctions is constructed in terms of electrochemical rate processes. Quantitative agreement with observations of the effects of depolarization, temperature, and osmotic pressure is obtained, and a quantitative interpretation of the Katz time lag is proposed.Keywords
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