Osteoporosis in neurological disorders

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Abstract
To date there have been no prospective case-control studies of fracture risk in neurological conditions. However, there are good reasons why some neurological patients may be at particular risk of osteoporosis and fracture. Although the aetiology of osteoporosis is multifactorial (with genetic factors accounting for 70% of the variability in bone density) exposure to high dose corticosteroids and poor mobility are two important potential causes. In addition, epileptics are a separate group at particular risk of fracture.

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