FATAL PULMONARY BLEOMYCIN TOXICITY IN CISPLATIN-INDUCED ACUTE-RENAL-FAILURE

  • 1 January 1980
    • journal article
    • research article
    • Vol. 64  (8-9) , 921-924
Abstract
A 53 yr old [human] male being treated for a metastatic squamous cell carcinoma had fatal pulmonary toxicity as a result of bleomycin therapy. The toxic reaction was observed when the conventional dose regimen of bleomycin was given to the patient who had unrecognized cisplatin-induced acute renal failure. Bleomycin dosage should be reduced in patients with established acute renal failure; the combination of cisplatin and bleomycin should be carefully followed.