2′,3′-Dideoxyadenosine Analogs of the Nucleoside Antibiotics Tubercidin, Toyocamycin and Sangivamycin
- 1 January 1989
- journal article
- research article
- Published by Taylor & Francis in Nucleosides, Nucleotides and Nucleic Acids
- Vol. 8 (1) , 97-115
- https://doi.org/10.1080/07328318908054160
Abstract
Application of previously described methodologies, for the synthesis of 2′,3′-dideoxy-2′,3′-didehydro nucleosides from the parent ribonucleosides, to the antibiotics tubercidin (1), toyocamycin (6) and sangivamycin (10) has provided the corresponding 2′,3′-unsaturated nucleosides 4, 9, and 13. A reduction of the 2′,3′-unsaturated moiety has afforded the 2′,3′-dideoxynucleoside antibiotics 5, 14, and 15.This publication has 16 references indexed in Scilit:
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