The pharmacology of non-steroidal anti-inflammatory drugs for acute pain
- 1 October 1995
- journal article
- pain therapy
- Published by Wolters Kluwer Health in Current Opinion In Anesthesiology
- Vol. 8 (5) , 461-468
- https://doi.org/10.1097/00001503-199510000-00018
Abstract
A central mode of action for non-steroidal anti-inflammatory drugs (in addition to the peripheral effects) now seems certain. A greater understanding of enantiomer pharmacology may lead to the development of safer drugs. The discovery of an inducible cyclo-oxygenase offers additional insight into non-steroidal anti-inflammatory drug activity. The need for research into non-steroidal anti-inflammatory drug toxicity in surgical patients is now more urgent than ever.Keywords
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