Diabetogenic Action of Analogues of 8-Hydroxyquinoline

Abstract
6-Hydroxy - m - phenanthroline and 1-hydroxyacridine caused hyperglycemia and destructive changes of the pancreatic islet in rabbits. 5-Hydroxybenzo-f-quinoline also produced a considerable hyperglycemia. However, 3 derivatives of pteridine, picolinic acid and dipicolinic acid failed to produce significant changes in blood sugar.