Steroids and related products. LII.11-Aza steroids. Part IV. The synthesis of 11-aza 9α-steroids. II. The synthesis of 11-aza-4,5α-dihydrotestosterone
- 1 March 1985
- journal article
- research article
- Published by Canadian Science Publishing in Canadian Journal of Chemistry
- Vol. 63 (3) , 766-772
- https://doi.org/10.1139/v85-126
Abstract
An efficient synthesis from adrenosterone or 11α-hydroxytestosterone of 17β-hydroxy-11-aza-5α-androstan-3-one, the 11-aza analogue of dihydrotestosterone, is described. For the elaboration of the 11-aza structure, a pathway implying a Curtius-type rearrangement of a 9,11-seco 9-oxo 11-acid was employed.This publication has 2 references indexed in Scilit:
- Heterocyclic steroids. Part II. Synthesis of (±)-8-hydroxy-3-methoxy-11-aza-18-norestra-1,3,5(10),9(11)-tetraen-17-one and related compoundsJournal of the Chemical Society, Perkin Transactions 1, 1976
- The Preparation of Desoxycorticosterone Acetate from 3-Keto-▵4-etiocholenic AcidJournal of the American Chemical Society, 1948