A CONVENIENT SYNTHESIS OF DL-ORNITHINE
- 1 November 1953
- journal article
- Published by Canadian Science Publishing in Canadian Journal of Chemistry
- Vol. 31 (11) , 1060-1063
- https://doi.org/10.1139/v53-139
Abstract
DL-Ornithine is readily prepared in a 68% yield by condensing 3-bromopropylphthalimide with ethyl acetamidocyanoacetate and by hydrolyzing the resulting 2-acetamido-2-carbethoxy-5-phthalimidovaleronitrile into DL-ornithine, isolated as the monohydrochloride. 3-Bromopropylphthalimide is obtained in a 57% yield from 3-aminopropanol by reaction with phthalic anhydride, followed by phosphorus tribromide.Keywords
This publication has 1 reference indexed in Scilit:
- b-BROMOETHYLPHTHALIMIDEOrganic Syntheses, 1952