Thiol protecting agents and antioxidants inhibit the mitochondrial permeability transition promoted by etoposide: implications in the prevention of etoposide-induced apoptosis
- 19 April 2002
- journal article
- Published by Elsevier in Chemico-Biological Interactions
- Vol. 140 (2) , 169-184
- https://doi.org/10.1016/s0009-2797(02)00020-0
Abstract
No abstract availableKeywords
This publication has 47 references indexed in Scilit:
- Mitochondrial permeability transition induced by the anticancer drug etoposidePublished by Elsevier ,2001
- Distinct Pathways for Stimulation of Cytochrome cRelease by EtoposideJournal of Biological Chemistry, 2000
- Ordering of ceramide formation, caspase activation, and Bax/Bcl-2 expression during etoposide-induced apoptosis in C6 glioma cellsCell Death & Differentiation, 2000
- Distinct stages of cytochrome c release from mitochondria: evidence for a feedback amplification loop linking caspase activation to mitochondrial dysfunction in genotoxic stress induced apoptosisCell Death & Differentiation, 2000
- Apoptosis, in human monocytic THP.1 cells, results in the release of cytochrome c from mitochondria prior to their ultracondensation, formation of outer membrane discontinuities and reduction in inner membrane potentialCell Death & Differentiation, 1998
- PK11195, a Ligand of the Mitochondrial Benzodiazepine Receptor, Facilitates the Induction of Apoptosis and Reverses Bcl-2-Mediated CytoprotectionExperimental Cell Research, 1998
- Disruption of the outer mitochondrial membrane as a result of large amplitude swelling: the impact of irreversible permeability transitionFEBS Letters, 1998
- The apoptosis-necrosis paradox. Apoptogenic proteases activated after mitochondrial permeability transition determine the mode of cell deathOncogene, 1997
- Characterization of free radicals produced during oxidation of etoposide (VP-16) and its catechol and quinone derivatives. An ESR studyBiochemistry, 1989
- Etoposide (VP-16–213)New England Journal of Medicine, 1985