REPRODUCTIVE-PERFORMANCE IN WOMEN WITH SEX-CHROMOSOME MOSAICISM
- 1 January 1980
- journal article
- research article
- Vol. 55 (5) , 608-611
Abstract
Among chromosomal analyses performed in 23 couples with a history of 2 or more spontaneous abortions, 5 women had mosaicism of the sex chromosomes, 46XX/47XXX but all the men had normal 46XY chromosomal complements. Of the fetuses of mothers with sex chromosome mosaicism, 75% were abnormal. Of these pregnancies, 50% ended in abortion and 1/3 of the infants exhibited a chromosomal or physical abnormality. The possible effect of sex chromosome mosaicism on outcome of pregnancy is emphasized.This publication has 5 references indexed in Scilit:
- A cytogenetic study of spontaneous abortions in HawaiiAnnals of Human Genetics, 1978
- Cytogenetics of Recurrent AbortionsFertility and Sterility, 1978
- A cytogenetic survey of 14,069 newborn infants: II. Preliminary clinical findings on children with sex chromosome anomaliesClinical Genetics, 1976
- Association of D/D translocations with fetal wastage and aneuploidy. A report of four families.Journal of Medical Genetics, 1976
- CHROMOSOME STUDIES IN COUPLES WITH REPEATED SPONTANEOUS ABORTIONS1976