Immunoelectrophoretic Demonstration of Specific Circulating Antigen in Animals Infected with Schistosoma Mansoni *
- 1 September 1967
- journal article
- Published by American Society of Tropical Medicine and Hygiene in The American Journal of Tropical Medicine and Hygiene
- Vol. 16 (5) , 606-612
- https://doi.org/10.4269/ajtmh.1967.16.606
Abstract
Summary With the techniques of immunoelectrophoresis, circulating antigen was demonstrable in the plasma of mice massively infected with Schistosoma mansoni. The reactant material appeared in the immunoelectropherogram as a specific anodic line, and its appearance was correlated with worm burden and duration of the infection. Experimental evidence was obtained that the antigen was not host-related. That the circulating antigen was of schistosomal origin was shown by comparative immunoelectrophoretic analyses of schistosomal homogenates and by appropriate absorption procedures.Keywords
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