Recommended Methods for Radioisotopic Erythrocyte Survival Studies: International Committee for Standardization in Hematology
- 1 July 1972
- journal article
- research article
- Published by Oxford University Press (OUP) in American Journal of Clinical Pathology
- Vol. 58 (1) , 71-80
- https://doi.org/10.1093/ajcp/58.1.71
Abstract
An Expert Panel † on the Application of Radioisotopes in Hematology, of the International Committee for Standardization in Hematology, has published recommended methods for erythrocyte survival studies using radioisotopes. This document includes standard technics using 51Cr and radioactive di-isopropylphosphorofluoridate (DFP). It also contains proposals for presentation and analysis of the data and a table of elution correction factors for use when the erythrocyte survival study has been carried out with 51Cr. The Panel has recommended that the use of a single index of should be discontinued and in all cases the mean cell life should be deduced. The document contains recommendations concerning the use of radioisotope labelled erythrocytes in compatibility testing. Estimates of radiation dose associated with erythrocyte survival studies are presented.Keywords
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