Cocaine and Vasospasm

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Abstract
Clinical reports published over the past decade have established the fact that recreational abuse of cocaine may result in acute myocardial infarction.1 At least 58 cases of acute myocardial infarction temporally related to cocaine abuse have been reported in the English-language literature. The results of selective coronary angiography have been reported in 45 of these 58 cases. In most, angiography was performed after the infarction and showed no evidence of narrowing of the coronary arteries. When performed very soon after the infarction, angiography has typically revealed thrombotic occlusion,2 with no residual narrowing after thrombolytic therapy. These findings have suggested that . . .