The immunoglobulin class of autoantibody-containing cells in the gastric mucosa.

  • 1 December 1970
    • journal article
    • Vol. 19  (6) , 891-4
Abstract
Autoantibody to Castle's intrinsic factor in mucosal plasma cells in gastric biopsies of patients with pernicious anaemia has been shown to be of the IgG type, using a double-labelling technique. The role of IgG immunoglobulins compared with that of IgA immunoglobulins in the immune response to autoantigens and to foreign proteins in the gastrointestinal tract is discussed.