Narciclasine:1H- and13C-NMR Data and a New Improved Method of Preparation

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Abstract
Narciclasine (I), a well known, nonbasic metabolite occurring in some Amaryllidaceae species, possesses an interesting antimitotic activity. It is structurally related to lycorine, the main amaryllidaceae alkaloid, and it exhibits a surprisingly higher activity than lycorine and several of its synthetic and natural analogs in the inhibition of ascorbic acid biosynthesis in potato tuber slices. A previous study on lycorine structure-activity relationships showed that narciclasine had a very strong antibiotic activity when assayed on Corynebacterium fascians

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