Survival Time and Treatment Results of Patients with Disseminated Breast Cancer Especially after Adrenalectomy and Hypophysectomy

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Abstract
Advanced breast cancer patients, all undergoing adrenalectomy or hypophysectomy, had the following mean survival data: from diagnosis to death, 54.76 months; from dissemination to death, 26.5 months; after adrenalectomy, 5.04 months; after hypophysectomy, 8.28 months. Survival was identical in early and late ablative surgery. The whole survival period from dissemination to death was longer than in most reported series. Prognostic significant factors are: menstrual status, long cancer-free period and probably first type of recurrence, and number of organ systems involved. Liver metastases are not an absolute contraindication against ablative surgery. Importance of exact staging before each therapeutic approach is emphasized.

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