Resistant Urinary Infections Resulting from Changes in Resistance Pattern of Faecal Flora Induced by Sulphonamide and Hospital Environment
- 8 August 1970
- Vol. 3 (5718) , 305-309
- https://doi.org/10.1136/bmj.3.5718.305
Abstract
The faecal flora was studied in eight children admitted to hospital for treatment of a first urinary infection with sulphonamides. The original, sulphonamide-sensitive Escherichia coli organisms were found to disappear, to be replaced by other E. coli serotypes that were almost invariably resistant to sulphonamides. Some of these serotypes carried R-factors for multiple antibiotic resistance. Possibly some urinary infections with antibiotic-resistant organisms may be due to faecal organisms whose resistance has been changed by previous antibiotic treatment. Hence it is important to study the effects of individual antibiotics on the faecal flora.Keywords
This publication has 12 references indexed in Scilit:
- Urinary Tract Infections: Correlation Between Organisms Obtained Simultaneously from the Urine and Feces of Patients with Bacteriuria and PyuriaJournal of Urology, 1969
- Controlled Trial Comparing Effect of Two and Six Weeks' Treatment in Recurrent Urinary Tract InfectionBMJ, 1969
- TRANSFERABLE DRUG RESISTANCE AND OTHER TRANSFERABLE AGENTS IN STRAINS OF ESCHERICHIA COLI FROM TWO HUMAN POPULATIONSThe Lancet, 1968
- The Urethra and its Relationship to Urinary Tract Infection. II. The Urethral Flora of the Female with Recurrent Urinary InfectionJournal of Urology, 1968
- STUDIES OF URINARY TRACT INFECTIONS IN INFANCY AND CHILDHOOD X. Short or Long‐term Treatment in Girls with First or Second‐time Urinary Tract Infections Uncomplicated by Obstructive Urological AbnormalitiesActa Paediatrica, 1968
- Phylogenetic relationships of drug-resistance factors and other transmissible bacterial plasmids.1968
- Studies of urinary tract infections in infancy and childhoodThe Journal of Pediatrics, 1967
- The Transmissible Nature of the Genetic Factor in Escherichia coli that Controls Haemolysin ProductionJournal of General Microbiology, 1967
- TRANSFERABLE R FACTORS IN ENTERIC BACTERIA CAUSING INFECTION OF THE GENITOURINARY TRACTThe Lancet, 1966
- THE EPIDEMIOLOGY OF NON-ENTERIC ESCHERICHIA COLI INFECTIONS: PREVALENCE OF SEROLOGICAL GROUPS*Journal of Clinical Investigation, 1962