Berberine Sulfate Inhibits Tumor-Promoting Activity of Teleocidin in Two-Stage Carcinogenesis on Mouse Skin
- 1 January 1986
- journal article
- research article
- Published by S. Karger AG in Oncology
- Vol. 43 (2) , 131-134
- https://doi.org/10.1159/000226349
Abstract
Berberine sulfate, an isoquinoline alkaloid isolated from Hydrastis canadensis L., inhibited the effects of the tumor promoters 12–O-tetradecanoylphorbol-13-acetate and teleocidin, such as increased 32Pi-incorporation into phospholipids of cell membrane and hexose transport. Berberine sulfate also markedly suppressed the promoting effect of teleocidin on skin tumor formation in mice initiated with 7,12-dimethyl-benz[a]anthracene.Keywords
This publication has 7 references indexed in Scilit:
- Inhibition of 12-O-tetradecanoylphorbol-13-acetate-stimulated 3-O-methyl-glucose transport in mouse Swiss 3T3 fibroblasts by glycyrrhetic acidCancer Letters, 1984
- Enhanced incorporation of radioactive inorganic phosphate into phospholipids of HeLa cells by tumor promotersCarcinogenesis: Integrative Cancer Research, 1983
- Teleocidin from Streptomyces is a potent promoter of mouse skin carcinogenesisCarcinogenesis: Integrative Cancer Research, 1982
- Inhibition of mouse skin tumor promotion by several inhibitors of arachidonic acid metabolismCarcinogenesis: Integrative Cancer Research, 1982
- Four fluorochromes for the demonstration and microfluorometric estimation of RNAHistochemistry and Cell Biology, 1981
- Microfluorometric investigations of chromatin structureHistochemistry and Cell Biology, 1981
- Fluocinolone acetonide: A potent inhibitor of mouse skin tumor promotion and epidermal DNA synthesisChemico-Biological Interactions, 1977