bcr Rearrangement without juxtaposition of c-abl in chronic myelocytic leukemia.
Open Access
- 1 December 1985
- journal article
- research article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 162 (6) , 2175-2179
- https://doi.org/10.1084/jem.162.6.2175
Abstract
Southern blot analysis detected a bcr gene rearrangement within leukemic cells of a Philadelphia chromosome-negative chronic myelocytic leukemia (CML) patient that led to transcription of a novel 7.3 kb bcr RNA species. Participation of the c-abl oncogene in this genomic recombination could be ruled out by in situ hybridization studies and Northern blot analysis.This publication has 14 references indexed in Scilit:
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