THE ETIOLOGICAL SIGNIFICANCE OF BORDETELLA-BRONCHISEPTICA AND PASTEURELLA-MULTOCIDA IN ATROPHIC RHINITIS OF SWINE

  • 1 January 1981
    • journal article
    • research article
    • Vol. 33  (12) , 513-522
Abstract
B. bronchiseptica was found to cause atrophy of the nasal turbinates in pigs when inoculated soon after birth. Infection with B. bronchiseptica alone did not result in clinical atrophic rhinitis. Turbinate lesions induced by B. bronchiseptica seem to have a pronounced tendency to spontaneous healing. Pigs exposed first to B. bronchiseptica and thereafter to P. mullocida developed a severe atrophic rhinitis corresponding to the natural disease. The P. multocida strain used for this experiment was one producing a toxin causing necrosis in the skin of guinea pigs on intradermal injection. The effect of vaccination of sows against B. bronchiseptica during pregnancy was studied in pigs infected with B. bronchiseptica only and in pigs inoculated with both B. bronchiseptica and P. multocida. While protection against infection with B. bronchiseptica was not obtained, pigs born to vaccinated sows seemed partly protected against the damaging effect of the infection. After inoculation with both B. bronchiseptica and P. mallocida, pigs born to vaccinated sows had fewer nasal lesions than pigs born to unvaccinated sows. The mean daily weight gain was reduced in pigs with severe atrophic rhinitis.