Irritant and allergic reactions to topically applied Micatin® cream

Abstract
Miconazole nitrate (Micatin cream) is a potent antifungal agent. Few side effects have been reported with topical application. Ten patients who exhibited an intolerance to topical use of this drug are reported. Most of the reactions were irritant in nature but, in 2 instances, an allergic contact dermatitis was observed. Patch tests were positive to the cream base.