Response variability to analgesics: a role for non-specific activation of endogenous opioids
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- 15 February 2001
- journal article
- clinical trial
- Published by Wolters Kluwer Health
- Vol. 90 (3) , 205-215
- https://doi.org/10.1016/s0304-3959(00)00486-3
Abstract
Individual differences in pharmacokinetics and pharmacodynamics, the type of pain and the method of drug administration can account for the response variability to analgesics. By integrating a clinical and an experimental approach, we report here that another important source of variabilityKeywords
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