The Hypocalcemic Action of Colchicine
- 1 June 1972
- journal article
- other
- Published by The Endocrine Society in Endocrinology
- Vol. 90 (6) , 1589-1593
- https://doi.org/10.1210/endo-90-6-1589
Abstract
Colchicine, injected ip in doses of 0.05–0.2 mg/100 g caused significant hypocalcemia in intact and nephrectomized rats. Colchicine prevented the rise in serum calcium following the injection of parathyroid hormone to thyroparathyroidectomized animals. Studies with 45Ca indicated that colchicine produced hypocalcemia by suppressing bone resorption. (Endocrinology90: 1589, 1972)Keywords
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