Natural Genetic Transformation of Clinical Isolates of Escherichia coli in Urine and Water
Open Access
- 1 January 2002
- journal article
- Published by American Society for Microbiology in Applied and Environmental Microbiology
- Vol. 68 (1) , 440-443
- https://doi.org/10.1128/aem.68.1.440-443.2002
Abstract
Transfer of plasmid-borne antibiotic resistance genes in Escherichia coli wild-type strains is possible by transformation under naturally occurring conditions in oligotrophic, aquatic environments containing physiologic concentrations of calcium. In contrast, transformation is suppressed in nitrogen-rich body fluids like urine, a common habitat of uropathogenic strains. Current knowledge indicates that transformation of these E. coli wild-type strains is of no relevance for the acquisition of resistance in this clinically important environment.Keywords
This publication has 40 references indexed in Scilit:
- Gene transfer between bacteria within digestive vacuoles of protozoaFEMS Microbiology Ecology, 2006
- High efficiency transformation of Escherichia coli with plasmidsPublished by Elsevier ,2003
- Evidence for Extensive Resistance Gene Transfer among Bacteroides spp. and among Bacteroides and Other Genera in the Human ColonApplied and Environmental Microbiology, 2001
- Natural genetic transformation in the rumen bacteriumStreptococcus bovisJB1FEMS Microbiology Letters, 1999
- The Crisis in Antibiotic ResistanceScience, 1992
- Calmodulin and calcium mediated regulation in prokaryotesJournal of General Microbiology, 1992
- GENE TRANSFER BETWEEN DISTANTLY RELATED BACTERIAAnnual Review of Genetics, 1991
- Calcium in bacteria: a solution to which problem?Molecular Microbiology, 1991
- Transformation In Escherichia coli: Studies On The Role Of The Heat Shock In Induction Of CompetenceMicrobiology, 1983
- Transfer of drug-resistance plasmids by conjugation from nosocomial strains of Serratia marcescens to Escherichia coli in biological fluids of human originJournal of Hospital Infection, 1982