Sequence of the promoter -operator proximal region of the major leftward RNA of bacteriophage lambda
- 1 January 1975
- journal article
- Published by Oxford University Press (OUP) in Nucleic Acids Research
- Vol. 2 (9) , 1441-1458
- https://doi.org/10.1093/nar/2.9.1441
Abstract
The sequence of the first 149 nucleotides of the major leftward RNA of bacteriophage lambda has been determined. Preliminary sequence information was also obtained for a portion of the untranscribed area immediately upstream of the point on the template when RNA synthesis normally starts. Several restriction endonuclease sites, deletion endpoints, and single base changes have been localized within the sequence. The first potential translation initiation codon which is not followed by an in-phase termination codon is a GUG located 90 nucleotides from the transcription startpoint.Keywords
This publication has 25 references indexed in Scilit:
- Genetic regulatory mechanisms in the synthesis of proteinsPublished by Elsevier ,2010
- Analysis of endonuclease R-EcoRI fragments of DNA from lambdoid bacteriophages and other viruses by agarose-gel electrophoresis.1974
- The Nucleotide Sequence of the Lactose Messenger Ribonucleic Acid Transcribed from the UV5 Promoter Mutant of Escherichia coliProceedings of the National Academy of Sciences, 1973
- Structure of the λ OperatorsNature, 1973
- Nucleotide Sequences from Tryptophan Messenger RNA of Escherichia coli : The Sequence Corresponding to the Amino-Terminal Region of the First Polypeptide Specified by the OperonProceedings of the National Academy of Sciences, 1973
- RNA Synthesis Startpoints in Bacteriophage λ: Are the Promoter and Operator Transcribed?Nature New Biology, 1972
- A low molecular weight species of RNA synthesized early after induction of the prophage λJournal of Molecular Biology, 1971
- Chromatography of 32P‐Labelled Oligonucleotides on Thin Layers of DEAE‐CelluloseEuropean Journal of Biochemistry, 1969
- Transcriptional controls in developing bacteriophagesJournal of Cellular Physiology, 1969
- Nucleotide Sequence Analysis of an Enzymatically Synthesized RNA Corresponding to the 5'-Terminal Region of Q RNACold Spring Harbor Symposia on Quantitative Biology, 1969