A novel muramyl peptide derivative stimulates tumoricidal activity of macrophages and antibody production by B cells
- 10 August 1987
- journal article
- Published by Wiley in FEBS Letters
- Vol. 220 (1) , 93-97
- https://doi.org/10.1016/0014-5793(87)80882-7
Abstract
A novel analog of MDP, the 3′‐iodo‐4′‐azido‐L‐phenylalanine methyl ester derivative of N‐acetyl‐L‐alanyl‐D‐isoglutamine, has been prepared. This compound is capable of activating macrophages to the tumoricidal state and increasing the specific immune response of B cells. It thus appears to exhibit similar biological activities to MDP. Moreover, this compound is of potential interest for receptor photolabelling studies.Keywords
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