Palladium-Catalysed Vinylic Substitution of Dimethyl Esters of N-Alkoxycarbonylkainic Acids with Aryl Halides

Abstract
The palladium-catalysed reaction of dimethyl esters of N-alkoxycarbonylkainic acids with aryl halides in the presence of catalytic amounts of Pd(OAc)2 and of the n-Bu4NCl/NaHCO3 combination affords stereoselectively the corresponding E vinylic substitution products in satisfactory yield.

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