Abstract
SEATTLE, WASHINGTON-- Since 1999, Microsoft CEO Bill Gates and his wife Melinda have created the world9s largest philanthropy, with current assets of $24.2 billion, and improving the health of the world9s poor is at the top of its agenda. So far, the Bill and Melinda Gates Foundation has spent $2.5 billion on global health--more than twice the annual budget of the World Health Organization. The foundation has rearranged the public health universe so speedily that many have yet to comprehend the change.

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