Surface View of Pericytes on the Retinal Capillary in Rabbits Revealed by Scanning Electron Microscopy

Abstract
Retinal capillaries of the rabbit were treated with HCl and collagenase to visualize the pericytes attached to the stromal surface of the capillary walls under the scanning electron microscope. Two types of pericytes were distinguishable on the basis of shape and localization. Type I had a slightly bulged, fusiform cell body with a few, long, braching cytoplasmic processes. These cells were scattered mainly in the region of the true capillary. Type 2 possessed a rather flattened and polymorphic cell body from which radiated short irregular cytoplasmic processes. These cells, which tended to overlap, were present predominantly in the region of the pre- or postcapillary vessels in the capillary bed. Type 1 may be the precursors of the smooth muscle cells.

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