Histology of Chemically Induced Mesotheliomas in Mrc-wistar Rats
Open Access
- 1 November 1975
- journal article
- research article
- Published by SAGE Publications in Tumori Journal
- Vol. 61 (6) , 509-515
- https://doi.org/10.1177/030089167506100602
Abstract
Two peritoneal mesotheliomas were induced in rats during a carcinogenicity study of 1-nitroso-5,6-dihydrouracil (NO-DHU) injected intraperitoneally. A review of literature concerning experimental induction of such tumors indicated that they seldom produced with organic compounds and rarely occur spontaneously. In the present study, several reports of chemically induced mesotheliomas of the testes are analyzed and the diagnoses critically reviewed along with other differential diagnoses.Keywords
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