AUTOMATIC CHROMOSOME ANALYSIS .1. A SIMPLE METHOD FOR CLASSIFICATION OF B-GROUP AND D-GROUP CHROMOSOMES REPRESENTED BY BAND TRANSITION SEQUENCES
- 1 January 1980
- journal article
- research article
- Vol. 17 (3) , 183-190
Abstract
An approach was described for the automatic analysis of banded human B- and D-group chromosomes, represented by band transition sequences (BT-sequences), using Bayes formula in a simple way. The analysis considers the 14 BT-codes constituting the BT-sequence as being independent variables. Error rates of 6-8% in classification experiments and 3-4% in karyotyping experiments are clearly smaller than those reported by others using other methods. If the error rates of karyotyping are adjusted for errors in the basic material, they are reduced to 2-3%. The reason for the small error rate is presumably that the BT-sequences are superior to other methods for condensed band-pattern description. The method will be incorporated into a program system for automatic karyotyping.This publication has 5 references indexed in Scilit:
- Microphotometry of banded human chromosomes IIIClinical Genetics, 2008
- Description of chromosome banding patterns by band transition sequencesClinical Genetics, 1979
- VISUAL CLASSIFICATION OF BANDED HUMAN-CHROMOSOMES .3. CLASSIFICATION AND KARYOTYPING OF DENSITY PROFILES DESCRIBED BY BAND TRANSITION SEQUENCES1979
- Visual classification of banded human chromosomes: II. Classification and karyotyping of integrated density profilesAnnals of Human Genetics, 1977
- Visual classification of banded human chromosomes I. Karyotyping compared with classification of isolated chromosomesAnnals of Human Genetics, 1976