A Simple HPLC Method for the Analysis of Bile Acids

Abstract
A simple reversed-phase HPLC method has been developed for the analysis of various bile acids, conjugated or unconjugated. A differential refractive index detector and C-18 silica column were used with an aqueous-methanol mobile phase. This method is accurate to 0.5 nmol and provides a simple and convenient quantitative determination of bile acids in aqueous buffer solutions.

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