The synthesis of 2-amino-2-deoxyhexoses: D-glucosamine, D-mannosamine, D-galactosamine, and D-talosamine
- 1 February 1968
- journal article
- research article
- Published by Canadian Science Publishing in Canadian Journal of Chemistry
- Vol. 46 (3) , 401-403
- https://doi.org/10.1139/v68-064
Abstract
Methods for the preparation of the hydrochlorides of 2-amino-2-deoxy-D-glucose (D-glucosamine) and 2-amino-2-deoxy-D-mannose (D-mannosamine) from tri-O-acetyl-D-glucal and of 2-amino-2-deoxy-D-galactose (D-galactosamine) and 2-amino-2-deoxy-D-talose (D-talosamine) from tri-O-acetyl-D-galactal are described. The reactions involve addition of nitrosyl chloride to the acetylated glycal followed by conversion of the adduct to acetylated derivative of the 2-oximinohexose and reduction of the oxime to amine.This publication has 1 reference indexed in Scilit:
- Synthesis of 3,4,6-Tri-O-acetyl-2-oximino-α-D-hexopyranosidesCanadian Journal of Chemistry, 1968