Separation and Configuration ofSynandAntiIsomers of Testosterone Oxime
- 1 January 1978
- journal article
- research article
- Published by Taylor & Francis in Analytical Letters
- Vol. 11 (3) , 229-237
- https://doi.org/10.1080/00032717808059696
Abstract
The syn and anti isomers of testosterone oxime, prepared with hydroxylamine hydrochloride in pyridine were separated on sulfoethyl Sephadex LH-20 in methanol. The predominant isomer had the highest mobility on the cation exchanger and the longest retention time when analyzed as the trimethylsilyl ether derivative on a glass capillary column coated with SE-30. Proton NMR spectra showed that the major isomer had a 4-anti and the minor isomer a 4-syn configuration.Keywords
This publication has 11 references indexed in Scilit:
- Selective liquid chromatographic isolation procedure for gas chromatographic-mass spectrometric analysis of 3-ketosteroids in biological materialsJournal of Chromatography A, 1976
- The multicomponent analysis of conjugates of neutral steroids in urine by lipophilic ion exchange chromatography and computerised gas chromatography-mass spectrometryThe Journal of Steroid Biochemistry and Molecular Biology, 1976
- 0-(2,3,4,5,6-Pentafluorobenzyl)Hydroxylamine Hydrochloride as a Sensitive Derivatizing Agent for the Electron Capture Gas Liquid Chromatographic Analysis of Keto SteroidsJournal of Chromatographic Science, 1975
- Analysis of steroids by high resolution gas-liquid chromatography : I. Preparation of apolar columnsJournal of Chromatography A, 1972
- O-Butyloximes and O-Pentyloximes as Derivatives for the Study of Ketosteroids by Gas ChromatographyAnalytical Letters, 1972
- MO-TMS Derivatives of Human Urinary Steroids for GC and GC-MS StudiesAnalytical Letters, 1972
- Gas chromatographic and mass spectrometric studies of oximes derived from 20-oxosteroidsSteroids, 1970
- Formation and gas-liquid chromatographic behavior of isometric steroid ketone methoxime derivativesAnalytical Biochemistry, 1968
- Gas-liquid chromatographic separation of C19 and C21 human urinary steroids by a new procedureBiochimica et Biophysica Acta (BBA) - General Subjects, 1966
- L'aromatisation acido‐catalysée de l'oxime d'une cyclohexadiénoneHelvetica Chimica Acta, 1965