ROSO: optimizing oligonucleotide probes for microarrays
Open Access
- 22 January 2004
- journal article
- research article
- Published by Oxford University Press (OUP) in Bioinformatics
- Vol. 20 (2) , 271-273
- https://doi.org/10.1093/bioinformatics/btg401
Abstract
Summary: ROSO is software to design optimal oligonucleotide probe sets for microarrays. Selected probes show no significant cross-hybridization, no stable secondary structures and their Tm are chosen to minimize the Tm variability of the probe set. Availability: The program is available on the internet. Sources are freely available, for non-profit use, on request to the authors. Supplementary information:http://pbil.univ-lyon1.fr/rosoKeywords
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