Curcumin-Artemisinin Combination Therapy for Malaria
- 1 May 2006
- journal article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 50 (5) , 1859-60
- https://doi.org/10.1128/aac.50.5.1859-1860.2006
Abstract
Artemisinin and curcumin show an additive interaction in killing Plasmodium falciparum in culture. In vivo, 3 oral doses of curcumin following a single injection of alpha,beta-arteether to Plasmodium berghei-infected mice are able to prevent recrudescence due to alpha,beta-arteether monotherapy and ensure almost 100% survival of the animals.Keywords
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