Safe and Rapid Isolation of Pulmonary Veins Using a Novel Circular Ablation Catheter and Duty‐Cycled RF Generator
- 6 October 2009
- journal article
- clinical trial
- Published by Wiley in Journal of Cardiovascular Electrophysiology
- Vol. 20 (10) , 1097-1101
- https://doi.org/10.1111/j.1540-8167.2009.01501.x
Abstract
Ablation of atrial fibrillation (AF) has been one of the most difficult and time-consuming electrophysiological procedures. Due to the rapidly increasing demand for ablation procedures, technical advances would be helpful to reduce complexity and procedure time in AF ablation. Therefore, we investigated the feasibility of a single-catheter technique for pulmonary vein (PV) isolation utilizing a decapolar catheter combined with a duty-cycled, unipolar-bipolar radiofrequency (RF) generator. AF mapping and ablation was performed in 21 consecutive patients (mean age 59 +/- 12 years, 9 males) with paroxysmal AF (n = 17) and persistent AF (n = 4). The ablation catheter was forwarded to the LA via single-transseptal puncture. All electrodes were energized in 2 to 5 applications per vein, followed by segmental RF applications, as needed, to achieve electrical isolation. To assess left atrial anatomy for purposes of catheter manipulation, and later evaluate the possibility of asymptomatic PV-stenosis, CT or MR imaging was performed both prior to ablation and at 6-month follow-up. Isolation could be achieved in 85/86 veins (99%). Procedure time for ablation was 81 +/- 13 minutes, and fluoroscopy time was 30 +/- 11 minutes. There were no procedural complications. Success rate at 6 months was 86% (18/21). MR or CT imaging excluded asymptomatic PV-stenosis. Mapping and ablation of PVs can be performed in a safe and efficient manner using a single-catheter technique, with short procedure times and minimal learning curve. Thus, this system may be of high interest not only for high volume but all centers performing AF ablation.Keywords
This publication has 15 references indexed in Scilit:
- ACC/AHA/Physician Consortium 2008 Clinical Performance Measures for Adults With Nonvalvular Atrial Fibrillation or Atrial FlutterCirculation, 2008
- Electrophysiologic and Anatomic Characterization of Sites Resistant to Electrical Isolation During Circumferential Pulmonary Vein Ablation for Atrial Fibrillation: A Prospective StudyJournal of Cardiovascular Electrophysiology, 2007
- Electrophysiological Differences of the Spontaneous Onset of Paroxysmal and Persistent Atrial FibrillationPacing and Clinical Electrophysiology, 2007
- Secular Trends in Incidence of Atrial Fibrillation in Olmsted County, Minnesota, 1980 to 2000, and Implications on the Projections for Future PrevalenceCirculation, 2006
- Atrial Fibrillation Ablation: Reaching the MainstreamPacing and Clinical Electrophysiology, 2006
- Worldwide Survey on the Methods, Efficacy, and Safety of Catheter Ablation for Human Atrial FibrillationCirculation, 2005
- Secular trends in the prevalence of atrial fibrillation: The Framingham studyPublished by Elsevier ,2004
- A new approach for catheter ablation of atrial fibrillation: mapping of the electrophysiologic substrateJournal of the American College of Cardiology, 2004
- Pulmonary Vein Isolation for Paroxysmal and Persistent Atrial FibrillationCirculation, 2002
- Spontaneous Initiation of Atrial Fibrillation by Ectopic Beats Originating in the Pulmonary VeinsNew England Journal of Medicine, 1998