A novel micromanipulation technique for measuring the bursting strength of single mammalian cells
- 1 November 1991
- journal article
- biochemical engineering-short-contribution
- Published by Springer Nature in Applied Microbiology and Biotechnology
- Vol. 36 (2) , 208-210
- https://doi.org/10.1007/bf00164421
Abstract
Information about the bursting strength of animal cells is essential if the mechanisms of cell damage in bioreactors are to be understood, and if cell mechanical properties are ever to be related to cell structure and physiology. We have developed a novel cell compression technique that makes it possible to directly measure the bursting strength of single mammalian cells, and to infer information about cell mechanical properties.Keywords
This publication has 7 references indexed in Scilit:
- Mechanisms and kinetics of monoclonal antibody synthesis and secretion in synchronous and asynchronous hybridoma cell culturesJournal of Biotechnology, 1990
- Transient shear stresses on a suspension cell in turbulenceBiotechnology & Bioengineering, 1990
- A need for systematic investigations into the material properties of cultured animal cellsTrends in Biotechnology, 1989
- Shear sensitivity of cultured hybridoma cells (CRL-8018) depends on mode of growth, culture age and metabolite concentrationJournal of Biotechnology, 1988
- A technique for determining the shear sensitivity of mammalian cells in suspension cultureBiotechnology Techniques, 1987
- An Application of the Micropipette Technique to the Measurement of the Mechanical Properties of Cultured Bovine Aortic Endothelial CellsJournal of Biomechanical Engineering, 1987
- Shear stress effects on human embryonic kidney cells in VitroBiotechnology & Bioengineering, 1985