Structure and Reactivity Studies of 5-Methyl-1,5-dihydro-5-deazaisoalloxazinophane
- 5 November 1988
- journal article
- Published by Oxford University Press (OUP) in Chemistry Letters
- Vol. 17 (11) , 1861-1864
- https://doi.org/10.1246/cl.1988.1861
Abstract
The X-ray structure analysis established that in the reaction of 5-deazaisoalloxazinophane and MeMgBr the methyl group is incorporated into the axial C(5) position. The axial selectivity is in line with the stereochemical course observed for the reduction of this compound. The product having only Heq at C(5) is much less reactive than 1,5-dihydro-5-deazaisoalloxazinophane having both Heq and Hax.This publication has 6 references indexed in Scilit:
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