Factors Affecting Sensitivity and Specificity of Screening Mammography and MRI in Women with an Inherited Risk for Breast Cancer
- 22 June 2006
- journal article
- research article
- Published by Springer Nature in Breast Cancer Research and Treatment
- Vol. 100 (1) , 109-119
- https://doi.org/10.1007/s10549-006-9230-z
Abstract
The MRISC study is a screening study, in which women with an increased risk of hereditary breast cancer are screened by a yearly mammography and MRI, and half-yearly clinical breast examination. The sensitivity found in this study was 40% for mammography and 71% for MRI and the specificity was 95 and 90%, respectively. In the current subsequent study we investigated whether these results are influenced by age, a BRCA1/2 mutation, menopausal status and breast density.Keywords
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