A monkey antigen crossreacting with carcinoembryonic antigen, CEA
Open Access
- 30 September 1976
- journal article
- research article
- Published by Springer Nature in British Journal of Cancer
- Vol. 34 (4) , 341-345
- https://doi.org/10.1038/bjc.1976.176
Abstract
Normal monkey tissues were found to contain an antigen which crossreacts immunologically with the carcinoembryonic antigen (CEA) of the human digestive tract. The monkey antigen reacted with complete or partial identity to the normal crossreacting antigen (NCA) in humans when tested in immunodiffusion against anti-CEA or anti-NCA. Extracts of monkey tissues inhibited in radioimmunoassays measuring human NCA. It is possible that monkey foetuses and colonic tumours contain CEA.Keywords
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