Complete Resolution of Paget Disease of the Vulva With Imiquimod Cream
- 1 April 2008
- journal article
- case report
- Published by Wolters Kluwer Health in Journal of Lower Genital Tract Disease
- Vol. 12 (2) , 90-94
- https://doi.org/10.1097/lgt.0b013e31815a58a5
Abstract
Extra mammary Paget disease (EMPD) is a neoplastic disease of apocrine gland bearing skin. Surgical excision is the standard of care for EMPD; however, it is accompanied by recurrence in more than 60% of the patients. Recently, imiquimod cream has been reported to induce complete responses in primary or recurrent EMPD. We report on 2 women with vulva EMPD who achieved biopsy-confirmed resolution of their disease after topical application of imiquimod 5% cream.Keywords
This publication has 10 references indexed in Scilit:
- The outcomes of patients with positive margins after excision for intraepithelial Paget's disease of the vulvaPublished by Elsevier ,2014
- Treatment of Extramammary Paget Disease with Topical Imiquimod Cream: Case Report and Literature ReviewSouthern Medical Journal, 2006
- Extramammary Paget's disease: Surgical treatment with Mohs micrographic surgeryJournal of the American Academy of Dermatology, 2004
- Successful treatment of extramammary Paget's disease of the scrotum with imiquimod 5% creamClinical and Experimental Dermatology, 2003
- Successful treatment of recurrent extramammary Paget's disease of the vulva with topical imiquimod 5% creamJournal of the American Academy of Dermatology, 2003
- Treatment of primary limited cutaneous extramammary Paget's disease with topical imiquimod monotherapy: Two case reportsJournal of the American Academy of Dermatology, 2002
- Radiotherapy for Perianal Paget’s DiseaseClinical Oncology, 2002
- Paget's Disease of the Vulva: Pathology, Pattern of Involvement, and PrognosisGynecologic Oncology, 2000
- Paget's Disease of the Groin: Report of Seven CasesPlastic and Reconstructive Surgery, 1997
- Extramammary Paget's Disease of the VulvaGynecologic Oncology, 1995