Radioligand-Binding Assay Employing P-Glycoprotein-Overexpressing Cells: Testing Drug Affinities to the Secretory Intestinal Multidrug Transporter
- 1 January 1998
- journal article
- Published by Springer Nature in Pharmaceutical Research
- Vol. 15 (7) , 1001-1006
- https://doi.org/10.1023/a:1011965707998
Abstract
Purpose. To develop a rapid and reliable system for affinity determination of conventional as well as newly synthesized compounds to P-gp. Methods. The principles of radioligand-binding assay were...Keywords
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