The Effect of Restricted Intake of Carotene and Vitamin A on Psoriasis Vulgaris
- 19 June 1947
- journal article
- Published by Massachusetts Medical Society in New England Journal of Medicine
- Vol. 236 (25) , 933-937
- https://doi.org/10.1056/nejm194706192362503
Abstract
KNOWLEDGE concerning the etiology and pathophysiology of psoriasis vulgaris is limited. Certain characteristics of the disease are generally recognized, however. One of the main physiologic functions of the epidermis is the production of keratin necessary for the protection against and for the repair of injuries to the cutaneous system. In the skin of a psoriatic person the mechanism of keratinization fails whenever increased demands on the protective and reparative processes of the epidermis occur. Instead of completely keratinized cells, defectively cornified — that is, parakeratotic cells — are produced.1 2 3 The extent and degree of the parakeratosis are related to the . . .Keywords
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