The absorption of vitamin A in ruminants and rats

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Abstract
Bullocks, sheep and rats were dosed with 5000 I.U. of vit. A/kg. body wt. and slaughtered 1-24 hr. after dosing. On slaughter, vit. A was estimated in systemic and portal blood, and also in the lymph or lymphatic tissues obtained from glands of the intestinal and other regions of the body. In all 3 species, the lymph or lymph glands in the intestine contained considerably more vit. A in dosed than in un-dosed animals. The avg. values for sheep and bullocks after dosing were 4830 and 1500 I. U. of vit. A/100 ml., and 180 and 225 I. U./100 ml. for animals not dosed. This marked rise was not found in the body lymph after dosing, the concns. being only 52 and 175 I. U./100 ml., respectively. The major part of this absorption seems to take place in the upper part of the intestine. The vit. A content of portal blood and of systemic blood rose after dosing, but the avg. figures for the portal blood were, if anything, slightly lower than those for systemic.
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